Platelet-Rich Plasma in the Treatment of Chronic Knee Pain

We get a lot of questions about this technique for treating knee pain. Here’s a rundown of our strategy and latest studies.
Before considering PRP for your knee pain, you can first try more conventional treatment options. Exercise, treatment, distraction knee manipulation, steroid injection, acupuncture, low-level laser, weight loss, glucosamine supplements, and knee braces are all examples of conservative care. You could be a candidate for PRP if these options have failed to alleviate the pain. QC Kinetix (Hardy Oak)-Regenerative Medicine is one of the authority sites on this topic. 
What exactly is PRP?
PRP is a platelet-rich plasma protein concentrate extracted from whole blood that has been centrifuged to kill blood cells. Development factors and cytokines are more concentrated in it than in whole blood. PRP has been used to promote a rapid healing response in a variety of specialties. Plastic surgery, dentistry, orthopaedics, and dermatology are all examples of this. We use PRP for chronic knee pain in our clinic. PRP is plasma that contains far more platelets than normal blood. Platelet concentrations – and thus growth factor concentrations – can be 5 to 10 times higher (or richer) than usual. This could help you recover more quickly and with less pain.
What is the procedure for using PRP?
Drawing your blood, swirling it down in a centrifuge, and injecting platelet-rich plasma from your own blood into your knee is what PRP is all about. This is all done in the same office visit. The whole process takes about 45 minutes.
Several research on the effectiveness of PRP are currently being conducted.
Patients in a study comparing Hyaluronic Acid (also known as rooster cone) and PRP received either drug. While both groups improved, the PRP group had better results. The PRP community had more synovial hypertrophy and less swelling on ultrasound of the knee. Three times, two weeks apart, the knee was injected (Int J Rheum Dis. 2018 May;21(5):960-966).
There have been relatively few issues recorded in published data on the side effects of PRP, apart from knee soreness. Since you’re using your own platelets, there’s a low chance of an allergic reaction. The current review shows that platelet-rich plasma (PRP) is a safe and efficient treatment for knee osteoarthritis (Int J Rheum Dis. 2017 Nov;20(11):1612-1630).
Early knee osteoarthritis can be treated with only one injection rather than three, with a good result (Joints, 2017 Jun 5;5(1):2-6). We’ve seen some patients in our clinic who were able to get relief from their knee pain in just one visit rather than the usual three.
In patients with knee osteoarthritis, platelet-rich plasma therapy enhances discomfort, stiffness, and impairment considerably more than standard saline treatment. To improve muscle strength recovery, additional strength training is recommended (Am J Phys Med Rehabil. 2018 Apr;97(4):248-254). We’ve discovered that combining PRP care with exercise improves performance.
In the study, the PRP group (72.7 percent) had a higher percentage of relief among responses than the HA group (45.8 percent ) Similar findings have been seen in our office, with 70-75 percent of PRP patients reporting “strong to excellent” relief (Arthroscopy. 2018 May;34(5):1530-1540).
Another study published in the American Journal of Sports Medicine in 2013 found that PRP injections were more effective than saline injections in reducing knee osteoarthritis pain.